The origin of syphilis-still controversial?

Syphilis is a sexually transmitted disease caused by spiral-shaped bacterium, Treponema pallidum The disease has been known under many names during history, and has had a prominent role in history and literature for the last several hundred years.Since its recognition in 15th-century Europe as a new disease, syphilis has been the subject of great m

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Guideline-based bismuth quadruple therapy for helicobacter pylori infection in China: A systematic review and network meta-analysis.

BackgroundCurrently, quadruple therapy is unanimously recommended as the current first-line treatment option for Helicobacter pylori (H.Pylori) eradication.However, the drug composition of quadruple therapy is very complex, and the efficacy and safety between them is not clear.AimsTo compare the efficacy and safety of H.Pylori eradication regimens,

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